Cassia Occidentalis: Unlocking Weed’s Phytochemicals, Bioactivities, and Future Potential

Abstract

Cassia occidentalis, traditionally regarded as a weed, is gaining recognition for its pharmacological significance. Despite its ethnomedicinal history, it remains underexplored in pharmaceutical research. This review synthesizes its phytochemical profile, therapeutic applications, and potential in drug development. Studies reveal diverse bioactivities, including neuroprotective, hepatoprotective, anti-arthritic, and antimicrobial effects, with biosynthesized nanoparticles enhancing its efficacy. Computational studies further highlight its interactions with pharmacological targets, suggesting applications in metabolic and neurodegenerative disorders. However, concerns over hepatotoxicity, particularly in children, necessitate dose standardization and controlled formulations. Future research must focus on standardized extraction methods, pharmacokinetics, and clinical validation to harness its therapeutic potential while ensuring safety.

Keywords: Cassia occidentalis, bioactive compounds, drug development, traditional medicine, phytochemical, therapeutic potential, protective effects, toxicity.