RESEALED ERYTHROCYTE AS A SMARTER DRUG DELIVERY SYSTEM: A BRIEF OVERVIEW

Abstract

Present pharmaceutical modernization innovation era aimed toward the development of such a drug delivery system which could maximizes the drug targeting alongside high therapeutic effect for safe and effective management of disease by reducing the adverse effect of the drug. The substances that have mechanisms to enhance the delivery and therefore not compromising with the effectiveness of medicine are termed as novel drug carriers. Drug carriers are utilized in assorted drug delivery systems such as: Controlled-release technology to increase in-vivo drug actions, diminish drug metabolism and reduce drug toxicity. These cellular carrier offer a greater prospective advantages related to their ability to circulate throughout the body, zero order kinetics, reproducibility and simple preparation. Primary aim for the event of this drug delivery system is to form best use of therapeutic performance, minimize the unwanted side effects of drug, eco-friendly, doesn't stimulate any immune reaction, co-exist with living tissues, alongside high drug loading efficiency. Encouraging the use of Resealed Erythrocytes in drug delivery include numerous advantages like as incredible degree of biocompatibility, thorough biodegradability, non-existence of toxic product, manageable life-span, diminishing drug side effects etc.

Keywords: Resealed Erythrocytes, Controlled-release technology, drug targeting, cellular carrier, Biodegradability.